Well, I can certainly see appropriate reasons why dealing with Outsiders (or their equivalent) or messing with the timestream may be bad for the Universe, even in the kind of setting I like to have, so I'm open-minded to have cosmic mechanisms in place that deal negative consequences for that kind of shenanigans. On the other hand, I'm absolutely averse to any kind of equivalent for stuff like lethal magic, body or mind manipulation, or necromancy.
Aside from getting in the way of my preferred playstyle, it smacks too much of validating conventional Abrahamic morality as true cosmic law, and I really hate it. Anything that goes too far in RPG or fiction to make a theist vision of the world factually true and 'right' gets me annoyed, uncomfortable, and if anything sympathetic with Luciferian rebellion against Heavenly tyranny. Even if magic and the supernatural get added to a setting, I very much prefer them to remain impersonal or at least neutral about ethical issues, either in the sense of them not taking sides or of all stances being represented by appropriate agents and archetypes playing on a level playing field. Even with magic, the cosmos should remain aloof and uncaring, with no apparent meaning or purpose apart from what sapient minds project on it.
Either there are no true gods, or they are fallible Ascended sapients and/or incarnations of archetypes, and pretty much all conceivable examples of the latter exist at once, including all historical major pantheons. Either there is no real Supreme God, or it is very much a distant, unknowable, uncaring Cosmic Watchmaker, impersonal First Principle, or pantheist All. The Universe at large really does not care or take sides about what sapients do to themselves and each other, either with mundane tools or supernatural powers, nor it makes any real difference whether something gets done with one's hands or one's mind.
Therefore, I'm not averse to having some kind of control mechanism in place to deal with outlandish violations of the stuff the first five Laws of Magic deal with, such as out-of-control magical serial-killers, mind-rapists, or soul-stealers, but it should absolutely be a social, legal one, same as for the equivalent mundane crimes. In other words, I'm OK with the White Council or any equivalent body establishing a code of law to deal with egregious magical crimes and enforcing it with more or less the same efficiency as mundane law enforcement. Of course, only in the case such a Code provides and allows for any sensible justifications such as necessity, self-defence, open combat or duel, consent of the subject, and the like, and cares about issues such as purpose and consequences. In this context, I assume even plot-threatening stuff such as mind-reading or controlling important NPC may be dealt with as a violation of magical law.