Potentially it does disqualify it, if any hint of collusion could result in hades Vault in Marcone’s Bank from not backing onto the Vault in Hades Realm then having the same space used for a different purpose would do the same thing, especially if there is another candidate which doesn’t have that dual purpose.
There is also the point that both the Gatekeeper and the Winter Lady used the Never Never route to Demonreach. Neither has any known association with Hades or Tartarus, both have associations with Mab and Arctis Tor. Mab will leak information to find out those she cannot trust and wait for them to prove her right, she did this with Nameless, perhaps she did the same with Maeve and the back door to Demonreach, indeed the attack may have been an attempt to verify the information by Maeves allies as much as release Lea. It was shut to her after this, suggesting Mab’s game.
People might want Demonreach to back onto Tartarus, bur there is no evidence for this, but there is circumstantial evidence for Mab’s Ice Garden, by those who have used the route to get there.
So what hordes of world threating monsters and demons are imprisoned in Mab's garden? The only actual time it appears in the books, it's being used to hold Lea to cure her. We know that she punishes people there but it's mostly her vassals that displease her(most recently Nameless, Laplander and Harry in
The Law). I don't think anything she has would be more than a Nagloshi. Demonreach holds fallen Gods. It's Never Never analog is someplace with equivalent or greater prisoners in equa numbers. That doesn't have to be Tartarus but it should be in that league and Mab's place just isn't.
And once again this theory hangs on that direct Way from Arctic Tor that's
never been even inferred by the books. Yes, Peabody met someone
in Chicago, a known nexus of Ways, but where is it stated that it was Maeve and that they came from Arctis Tor? If an already Nemfected Maeve had known a Way to the island, she could have loosed the sleepers before Harry ever became Warden or Winter Knight. Rashiid says he knows a Way but we have no way to know where he started from. A spot that approaches the Outer Gates would seem to be a better choice.