I've run two games in DFRPG, one around a table and another here on these boards.

The first game was set in Austin, Texas and took place before the Vampire Wars. I kept that one mostly canon for the most part. Harry exists in Chicago as a lone practitioner. There is a Warden of the Southern US in Dallas, Texas who showed up occasionally as the situation demanded it. One of my players was the great-great-great-great-great-great-great-great Grandfather of Ancient Mai. He was a Wizard of the White Council and bound to a Phoenix who represented Yang. His enemy was a Sorceror who was bound to the Dragon Yin. The only time the two of them were on the same plane of existence is when it was time to determine which would be dominant. They would fight and the loser would be temporarily banished to an area of the NeverNever until the time for the next fight. Technically he was over 1200 years old, but because of his special pact with Yang, he would not die of natural age.
 
Another player wanted to play a Knight of the Cross so I used the Legend of the 4th Nail to give him a sword without changing the backstory for the canon world too much.  Then there was the quarter angel, quarter demon, half human who was destined to be the mother to the anti-christ. Oh yeah, and the son of a malk who became a Fairy Knight.

I also fleshed out Alternate Fae Courts from before the Fairy War (not the Changing of Seasons War that goes on every year, but the big war that banished the Fomor). The Shen in my game were a smaller court of Asian Fairies whose mantles passed through specific blood lines and were thus much easier to wipe out. A Shen Princess allied herself with the Seelie Court and after the first adventure had taken of residence in Austin. The Kong Apes didn't make an appearance, but it was mentioned by a Warden friend that it wasn't the first time the Shen had been encountered. Then there was the Chinese liquid metal demon, the Amtgard Spring War that turned into a Showdown with the Erlking, Dracula, the demon prince that almost managed to control the world because of the particular wording of an End User Agreement with Michael Dell (I mean honestly, who ever really reads those things). I had a lot of fun with that game.

The second game I'm running is set in World War 2 Europe. It's just starting out really (only been going on for a year in PbP) and is focused primarily in the Haute-Marne Prefecture of France. I'm planning on branching that out into a series of missions across Europe and Africa working for the Allies, but for now they've had an investigation into why there have been dozens of demonic possessions going on.

Water Block vs Sight.

There's a Dirk Diggler joke here too.

Fires a spray of Salt Water directly into the opponent's eyes blinding them temporarily.

Fire Skill Replacement for Moving through Zones.

Sure. It never hurts to have another set of eyes.

The Codex series is on my list of books to read, so I probably won't be any help. But there are other Codex fans here.

I don't know much about the series, but I've found a wiki. I'll try to break the magic it lists like they did.

Earth Witch - Probably a Nature-based Sponsored Magic. It seems to be heavy on thaumaturgy and less on evocation.

Ley Line Witch - I'd add Evocation, maybe with a limitation that it will only work near a leyline. Depending on the universe (which I know nothing about) that could be a minor or major limitation, giving a bonus anywhere from +1 to +2.

Demon Magic - The description screams of a Demonic Curse based Sponsored Magic with an Evothaum towards curses.

Seems she would have a high Stealth and Contacts. Maybe even a Stunt that has to do with Planning although I'm only basing that off of the wiki.

I'd build him similar to Marcone. He'd have a higher Rapport than Marcone just because of how he is portrayed on the show, always chatting about seemingly innocuous subjects to keep people off guard and building maneuvers and then tagging them for an Intimidate to get the piece of information he needs.

Defensive Spirit Maneuver

A burst of mental static hits an attacker making them pause for a crucial moment.

Transmutation zone wide evothaum attack

Zone wide Flesh to Stone spell. Does regular damage, but taken out turns those hit into statues. Consequences also reflect transformative nature of spell.

Divination evothaum attack.

Riding a platform of rock earthbender style.

Conjuration Investigation skill replacement

Conjuring a magnifying glass and deerstalker cap (cocaine habit is optional)

Soulfire evothaum maneuver Indirect attack

Paper magic Might skill replacement.

Magically ripping a phone book in half

Photomancy skill replacement for Crafting (I can play that game too)