Gentlemen, those are some very fine ideas. Thanks a lot for them!
PirateJack: Hm, that sounds interesting. The WC are no newcomers in Prague but they can still benefit from the tension between those two places. In my plans, the WC is a major wild player, influencing the history of Bohemia heavily, but on a subconscious level. They feed on conflict and discord => catholics vs. hussites and protestants, Czechs vs. Germans, Nazis vs. democrats, Communists vs. democrats, etc. All nourishing food for the WCVs. Btw., there is a brothel one tram stop away from 
Anděl and its name is 
Lilith. I have discovered that yesterday when I was walking through the area. And ... there is an old disused cemetery just next to the brothel and on the opposite side of the cemetery there is a small baroque church. (
click - the brothel is 
Erbenova Nr. 3 and on the south side of the cemetery in 
Duškova street there is a ventilation shaft pryed open) Ideas are flowing to my head :-)
Sanctaphrax: Yes, you are right, there is a major golem legend in Prague: 
click However, I haven´t decided on how to use it, yet. In one of 
Vampire: The Masquerade games I was a player in Rabbi Loew was the head of the Tremere and the Golem was his Gargoyle so I don´t want to push this stuff too much. But it certainly has a lot of potential.
Jreafman: I like your ideas. As for the towers - my basic idea is that they are creating a powerful pattern with Prague's 
Orloj as a centre point. This pattern, when complete and active, allows time manipulation. 
Click and 
click. And you are giving me more ideas. In 
Ďáblice there is an astronomical observatory (a tower!). Just next to 
Ďáblice is 
Kobylisy with a target range where the Nazis executed their prisoners. North of 
Ďáblice is 
Panenské Břežany, the seat of Reinhard Heydrich (
click) during WWII and just south of 
Ďáblice Heydrich was mortally wounded and died in a nearby hospital (
click). Both 
Anděl and 
Ďáblice have metro stations. I'm thinking about such a situation: there is a fallen angel in Prague. Not a Denarian, more like some of the characters from the film 
Wings of Desire (
click). And there is a she-devil, his counterpart, too. Both beings are fallen, crippled, not able to return back from where they had once come. Maybe they crippled each other during a fight a long time ago. They still have some power but can't use it on their own. Only mortals can tap into that for a brief time. Maybe both are just semi-conscious, lying underground, mentally aware of each other. Maybe they have come to terms with each other somehow, because of their state and unability to change that. Maybe they are playing some mental game of wits, using the city as their chessboard, manipulating both mortals and supernaturals into being their pawns...